A sad portrait of congenital syphilis in the State of Rio de Janeiro. Case report with Polymerase Chain Reaction (PCR) of scrapings from skin lesions and placenta fragment positive for Treponema pallidum

Introduction: Congenital syphilis is a serious public health problem that causes high rates of intrauterine morbidity and mortality, revealing flaws and weaknesses in the health system. Objective: to report a case of congenital syphilis in a university hospital in the Center-South Region of the State of Rio de Janeiro, Brazil. Case report: A pregnant woman, aged between 19 and 23 years old, carrying a Pregnant Woman's Handbook with a record of seven prenatal consultations and a note of the serological reaction for positive syphilis, but without any treatment, hospitalized at the University Hospital of Vassouras (RJ), in labor, gave birth to a newborn (NB) with a clinical picture and serological test of congenital syphilis. The NB required care in an intensive care unit and was discharged 28 days after birth. Scraping of skin lesions of the NB and placenta was performed for analysis by molecular biology (PCR in house) and genetic material of Treponema pallidum was detected. Conclusion: Congenital syphilis is a serious outcome of syphilis during pregnancy, consuming high financial resources and significant emotional distress for the mother, father, the whole family, as well as for the health teams. Our case report was the first that we are aware of in Brazil with a diagnosis by PCR for positive Treponema pallidum of skin scraping and placental fragment. It also showed poor quality prenatal care, a common factor in most cases of CS in our reality

Mpox transmitted through sexual intercourse: three case reports

Introduction: In 2022, many countries, such as Brazil, experienced outbreaks of mpox (formerly called monkeypox) in sexually active people with multiple sexual partners. Objective: Report cases of patients diagnosed with Mpox. Methods: Report three cases of patients diagnosed with Mpox treated at the STD Sector at Universidade Federal Fluminense. Results: We report three cases of young adult patients who spontaneously sought our STD service with wounds in the anogenital area, mouth and other parts of the body. These cases include a 28-year-old man (HIV positive) who had lesions on his penis and body, a 34-year-old man with perianal ulcers and adenopathy, and a 40-year-old man with painful ulcers on his penis. Conclusion: The article provides information on the symptoms, transmission, and prevention of mpox, highlighting the need for early detection, diagnosis, and prompt treatment to contain and prevent the spread of the disease. The cases presented in this study show all the characteristics of a sexually transmitted disease

Introdução: Em 2022, muitos países, como o Brasil, experimentaram surtos de mpox (anteriormente chamada de monkeypox) em pessoas sexualmente ativas com múltiplos parceiros sexuais. Objetivo: Relatar casos de pacientes diagnosticados com mpox. Métodos: Relatar três casos de pacientes com diagnóstico de mpox atendidos no Setor de Doenças Sexualmente Transmissíveis (DST) da Universidade Federal Fluminense (UFF). Resultados: Relatam-se três casos de pacientes adultos jovens que procuraram espontaneamente o Setor de DST da UFF com feridas na região anogenital, boca e outras partes do corpo. Esses casos incluem um homem de 28 anos (HIV positivo) que apresentava lesões no pênis e no corpo, um homem de 34 anos com úlceras perianais e adenopatia e um homem de 40 anos com úlceras dolorosas no pênis. Conclusão: O artigo fornece informações sobre os sintomas, transmissão e prevenção da mpox, destacando a necessidade de detecção precoce, diagnóstico e tratamento imediato para conter e prevenir a propagação da doença. Os casos apresentados apresentam todas as características de uma doença sexualmente transmissível.